Functional bowel disorders comprise a spectrum of chronic gastrointestinal (GI) disorders characterized by abdominal pain, bloating, distention, and/or bowel habit abnormalities (constipation, diarrhea, or mixed constipation and diarrhea) in the absence of any organic or biochemical pathology.1,2 These are primarily attributed to the deranged functioning of the well coordinated brain-gut axis that results in an array of symptoms that can affect any part of GI tract.3 Irritable bowel syndrome (IBS) is a highly prevalent functional bowel disorder characterized by symptoms of abdominal pain or discomfort that occur with changes in bowel function (Box 1).4-6 Based on stool consistency, the Rome IV criteria classify IBS into constipation-predominant IBS (IBS-C), diarrhea-predominant IBS (IBS-D), IBS alternating between constipation and diarrhea (IBS-M), or unclassified IBS (Box 2).