Biliary colic is the most common clinical presentation of symptomatic gallstone disease, and refers to acute biliary pain which occurs when the gallbladder contracts against any stone obstructing the cystic duct or common bile duct of the biliary tree. Patients with biliary colic usually complain of a sharp, steady or intermittent pain in the upper abdomen, mostly under the right side of the rib cage; it is frequently accompanied with nausea and vomiting.