Urinary tract infection (UTI) is one of the most common serious bacterial infections among the pediatric population. Indeed, pediatric UTI is a common cause of presentation to healthcare providers that makes it an important area of concern for parents and clinicians alike. Girls are more likely to be diagnosed with a UTI after first 12 months while about half the boys with UTI are likely to be diagnosed within the first 12 months of life. Prevalence and incidence further varies by age, race/ethnicity, sex and circumcision status. Children frequently present with complaints of fever, lethargy, anorexia, and vomiting, but UTIs may have several adverse consequences as well, especially in the young.