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Pedia Flash 2026 › Pedia Flash Ace Vol-11, No-1, 2026

Beyond Conventional Management: Establishing Lactase Enzyme Supplementation as an Evidence Based Intervention for Colic Relief

Infantile colic is a common condition characterized by unexplained, inconsolable crying episodes in otherwise healthy infants without any identifiable cause. It can lead to significant parental distress, increase the risk of child abuse, and contribute to early cessation of breastfeeding. According to Wessel’s criteria, also known as the “rule of threes,” colic is defined as episodes of irritability, fussing, or crying lasting at least 3 hours per day, on 3 or more days per week, for at least 1 week, in an otherwise healthy infant aged 2 weeks to 4 months.